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Bottle of Protandim NAD

Protandim® NAD Synergizer* Support


  • Vegetable-based capsules.

  • It is recommended to only use according to the directions on the label (two capsules per day).

  • No. We have not tested Protandim NAD Synergizer on pets and do not recommend giving it to our furry loved ones. We do recommend giving your pets Petandim, it’s a dog-friendly formulation.

  • Yes, Protandim NAD Synergizer is Vegetarian.

  • We do not expect there to be any side effects for the typical Protandim NAD Synergizer consumer. However, some individuals may have natural allergic responses or sensitivities to one or more of the ingredients, just as some people are allergic to pollen or penicillin. If you are experiencing any adverse reaction, discontinue use of the product and call Distributor Support at 1 (866) 460-7241.


  • As with any supplement, particularly if you have a medical condition and are taking medication or other supplements, you should speak with your healthcare provider before taking Protandim NAD Synergizer. If you experience nausea, vomiting, diarrhea or any other difficulties after taking Protandim NAD Synergizer, discontinue use and consult your healthcare provider.

  • The shelf life for Protandim NAD Synergizer is two years from the date of manufacture.


  • Some of the active ingredients in Protandim NAD Synergizer are fat soluble, so taking Protandim NAD Synergizer with a meal containing some fat allows the ingredients to be absorbed more efficiently (but it’s not absolutely necessary).


  • Yes! Protandim NAD Synergizer does not contain any banned or controlled substances. The BSCG symbol will be added to the Protandim NAD Synergizer label after the first production is tested. The BSCG logo will assure consumers that every lot of Protandim NAD Synergizer has been analyzed and certified by the Banned Substances Control Group (BSCG) to be free of all substances banned by the World Anti-Doping Agency (WADA).

  • Protandim NAD Synergizer will be certified by NSF International after our product is tested. Certification by NSF means that an independent organization has reviewed the manufacturing process of a product and determined that the final product complies with specific standards for safety, quality or performance. NSF certification is recognized by regulatory agencies at the local, state, federal and international level, and NSF periodically conducts audits and product testing to verify that the product continues to comply with the standard.

  • The FDA does not approve dietary supplements, however, companies must follow all regulations and submit a notification to the FDA within the first month of marketing a new product. Additionally, manufacturers and distributors must ensure all claims and information on the product label and any other labeling are truthful and not misleading. Under FDA regulations, all domestic and foreign companies that manufacture, package, label or hold dietary supplements, including those involved with testing, quality control, and dietary supplement distribution in the U.S., must comply with current Good Manufacturing Practices (cGMPs) for dietary supplements.

  • Protandim NAD Synergizer is 100% Vegetarian, free from gluten, wheat, dairy, gelatin and yeast. The ingredients in Protandim NAD Synergizer are naturally derived or bio-identical ingredients.

  • No, there are no dyes or food colorings in Protandim NAD Synergizer.


  • All Protandim NAD Synergizer manufacturers are required to maintain a strict allergen program to protect against any potential cross contamination of allergens. These facilities are frequently audited to ensure that the processes and protocols are being strictly adhered to to ensure the safety of the product.

  • The raw ingredients are tested, carefully weighed out, blended and packed into capsules following strict Good Manufacturing Practices (GMP) guidelines. Every lot of finished Protandim NAD Synergizer is tested for compliance to approved specifications in addition to receiving a final quality inspection following dietary supplement regulations. Every lot must, meet or exceed established finished product specifications before it can be released by LifeVantage Quality Assurance.

  • No, the individual ingredients in Protandim NAD Synergizer aren’t as effective in supporting the expression of genes that are part of the signaling pathways to activate the NAD dependent enzymes as LifeVantage’s botanical blend.* For best results, it is recommended to take the entire Protandim line.

  • Yes, we perform exhaustive testing to verify that all LifeVantage products meet or exceed quality standards. The Quality Control measures implemented by LifeVantage exceed industry standards. We rigorously test every lot of product for identity, potency, microbial contamination, pesticides and heavy metals, and physically audit manufacturing facilities and raw material suppliers.

  • No, we do not recommend this product for children. Our products are made for individuals 18 years-of-age and older. This product should not be taken by children.


  • No, we do not recommend this product if you are pregnant or nursing.

  • Yes.

  • Yes.

  • Please consult your physician if you are taking any medication before use.

  • Yes.

  • The suggestion is for adults to take two capsules daily. No specific time is recommended. It is recommend not to take within six hours of bedtime.

  • Researchers and scientists agree that aging is the natural result of overall cellular deterioration. One major way this occurs is through exposure to free radicals, other oxidants, and toxicological insults. It is impossible to avoid these exposures because the food you eat, the air you breathe, our modern lifestyles, stress, and even exercise, but we can do certain things to maintain our health as we age. The human body naturally fights these insults by producing its own antioxidant and detoxification enzymes through Nrf2-dependent mechanisms. However, as we grow older, Nrf2 works less efficiently. That’s where Protandim® Nrf2 Synergizer TM plays a critical role. It supports these Nrf2-dependent mechanisms to boost the body’s production of antioxidant and detoxification enzymes. Another natural phenomenon relating to the aging process is our mitochondria (the cell’s powerplant) begins working less efficiently. Less efficient mitochondria produce less energy and produce excess free radicals and other oxidants. Supporting overall mitochondrial function is important to promote overall health as we age. Protandim NRF1 was designed to both increase mitochondrial number and provide ingredients shown to support mitochondrial health. Lastly, another major significant effect of the aging process is a decline of cellular NAD levels and reduction of sirtuin activity. Sirtuin activity has been shown to play a major role in supporting overall health. Protandim® NAD Synergizer TM was designed to support NAD levels and sirtuin activity. Thus, taking the entire Protandim family of products will help support all of these significant aspects of the aging process.*

  • NAD is essential for sirtuin activity throughout the entire body and sirtuin activity declines with age. Protandim® NAD Synergizer TM supports the expression of genes that are part of signaling pathways to activate NAD-dependent enzymes and increase sirtuin activity. Therefore moving beyond NAD and into the real goal–sirtuin activity.

  • NAD is the abbreviation for Nicotinamide Adenine Dinucleotide.

  • Yes! The Axio products are designed to improve both physical and mental energy levels, while Protandim is designed to reduce cellular stress by activating the body’s protective Nrf2-pathway. Since the AXIO products contain several ingredients with known Nrf2-activating effects (Green tea extract, New Zealand pine park extract, and Quercetin), it is recommended to consume Protandim and AXIO at least one hour apart from each other, and ideally up to two hours apart, for optimal absorption and efficacy of each product.

    For example, many people prefer to take their Protandim with breakfast or another meal to optimize absorption, while the AXIO is typically used between meals to maintain physical energy, mental focus, and overall well-being. Even though the AXIO contains several ingredients with Nrf2-activating effects, these ingredients are quite different from the ingredients in Protandim (even the green tea extracts are very different between products, with different methods of extraction and different bioactive polyphenol profiles). The Protandim formula has been optimized to provide Nrf2-synergy between each of it’s five individual ingredients, while the AXIO has been optimized to provide a multi-dimensional energy boost for both body and mind.


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